By Anthony E. Redington, Alyn H. Morice
A entire evaluation of the clinical and scientific elements of acute and persistent cough, this reference specializes in fresh advancements in our realizing of the molecular biology of putative cough receptors, the neural mechanisms thinking about the afferent and efferent limbs, the principal processing of the cough reflex, and peptides and different components that can mediate or modulate the cough reflex. With chapters written via said experts within the box, this instruction manual covers present and strength healing brokers, a variety of methodologies to degree cough reflex sensitivity, and scientific methods for the evaluation of persistent cough in adults and youngsters.
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RARs are differentiated from other airway afferent nerves by their rapid (1–2 sec) adaptation to sustained lung inflations (Fig. 2) (13–19). Other distinguishing properties of RARs include their sensitivity to lung collapse and/or lung deflation, their responsiveness to alterations in dynamic lung compliance (and thus their sensitivity to bronchospasm), and their conduction velocity (4–18 m/sec, suggestive of small myelinated axons) (11–21). 5 No No Yes Yes Sparse Yes Yes Yes Yes Low Low High Activated Increased Inactivated No effect No effect Increased No effect Increased Increasedb Increasedb Decreased No effect No effect No effect Increased Increased Increasedc Increasedc Excitatory Hyperpnea No Inhibitory Inhibit inspiration No Excitatory Apnea Yes a Typical attributes of the afferent nerve subtypes are listed.
Xu H, Zhao H, Tian W, Yoshida K, Roullet JB, Cohen DM. Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR253 mediates its response to hypotonic stress. J Biol Chem 2003; 278: 11520–11527. Vlachova V, Teisinger J, Suankova K, Lyfenko A, Ettrich R, Vyklicky L. Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1. J Neurosci 2003; 23:1340–1350. Chyb S, Raghu P, Hardie RC.
Rescue of the Drosophila phototransduction mutation trp by germline transformation. Science 1985; 230: 1040–1043. 29. Gunthorpe MJ, Benham CD, Randall A, Davis JB. The diversity in the vanilloid (TRPV) receptor family of ion channels. Trends Pharmacol Sci 2002; 23:183–191. 30. Bevan S, Geppetti P. Protons: small stimulants of capsaicin-sensitive sensory nerves. Trends Neurosci 1994; 17:509–512. 31. Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sorgard M, Di Marzo V, Julius D, Hogestatt ED. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide.
Acute and Chronic Cough by Anthony E. Redington, Alyn H. Morice